| 2022-02-13 13:00:00Sun., Feb 13 | Penn State | 4 - 2 | Ohio State | Ohio State University Ice Arena | Recap |
| 2022-02-12 20:40:00Sat., Feb 12 | Stevenson | 1 - 3 | Navy | McMullen Ice Arena | Recap |
| 2022-02-12 17:30:00Sat., Feb 12 | Millersville | 4 - 5 | Delaware | Fred Rust Arena | Recap |
| 2022-02-12 17:30:00Sat., Feb 12 | Maryland | 3 - 0 | Towson | McMullen Ice Arena | Recap |
| 2022-02-12 14:30:00Sat., Feb 12 | Rowan | 1 - 3 | Indiana (Pa.) | S&T Bank Arena | Recap |
| 2022-02-12 13:30:00Sat., Feb 12 | Penn State | 4 - 6 | Cincinnati | Sports Plus Cincinnati | Recap |
| 2022-02-11 20:30:00Fri., Feb 11 | Penn State | 3 - 5 | Cincinnati | Sports Plus Cincinnati | Recap |
| 2022-02-11 20:30:00Fri., Feb 11 | Maryland | 0 - 4 | Navy | McMullen Ice Arena | Recap |
| 2022-02-11 20:15:00Fri., Feb 11 | West Chester | 1 - 12 | Rider | Loucks Ice Center | Recap |
| 2022-02-11 20:00:00Fri., Feb 11 | Rowan | 7 - 5 | Indiana (Pa.) | S&T Bank Arena | Recap |
| 2022-02-11 17:30:00Fri., Feb 11 | Stevenson | 5 - 3 | Towson | McMullen Ice Arena | Recap |
| 2022-02-05 20:45:00Sat., Feb 5 | Liberty | 0 - 3 | Florida Gulf Coast | Hertz Arena | Recap |
| 2022-02-04 20:45:00Fri., Feb 4 | Liberty | 1 - 3 | Florida Gulf Coast | Hertz Arena | Recap |
| 2022-01-30 17:30:00Sun., Jan 30 | George Washington | 17:30:00Postponed | Drexel | Class of 1923 Arena | Recap |
| 2022-01-30 00:00:00Sun., Jan 30 | Penn State | 00:00:00Postponed | West Chester | Ice Line | Recap |
| 2022-01-28 00:00:00Fri., Jan 28 | Georgetown | 4 - 1 | Maryland | The Gardens Ice House | Recap |
| 2022-01-23 15:15:00Sun., Jan 23 | Liberty | 3 - 5 | Sault College | Goggin Arena | Recap |
| 2022-01-23 00:00:00Sun., Jan 23 | Xavier | 00:00:00Postponed | Maryland | The Gardens Ice House | Recap |
| 2022-01-22 21:00:00Sat., Jan 22 | Xavier | 21:00:00Postponed | Maryland | The Gardens Ice House | Recap |
| 2022-01-22 20:15:00Sat., Jan 22 | Stockton | 6 - 10 | Rowan | Hollydell Ice Arena | Recap |
| 2022-01-22 17:25:00Sat., Jan 22 | Liberty | 8 - 1 | Davenport | Goggin Arena | Recap |
| 2022-01-22 16:15:00Sat., Jan 22 | Towson | 8 - 1 | Stevenson | Reisterstown Sportsplex | Recap |
| 2022-01-21 21:05:00Fri., Jan 21 | Georgetown | 3 - 2 | Stevenson | Reisterstown Sportsplex | Recap |
| 2022-01-21 14:15:00Fri., Jan 21 | Liberty | 3 - 1 | Cincinnati | Goggin Arena | Recap |
| 2022-01-21 00:00:00Fri., Jan 21 | St. Joseph’s | 0 - 8 | Rider | Loucks Ice Center | Recap |
| 2022-01-16 15:35:00Sun., Jan 16 | Rowan | 7 - 2 | New Jersey | Loucks Ice Center | Recap |
| 2022-01-15 20:30:00Sat., Jan 15 | Delaware | 7 - 5 | Millersville | Lancaster Ice Arena | Recap |
| 2022-01-15 20:15:00Sat., Jan 15 | William Paterson | 3 - 2 | Rider | Loucks Ice Center | Recap |
| 2022-01-14 21:20:00Fri., Jan 14 | Millersville | 21:20:00Cancelled | Delaware | Fred Rust Arena | Recap |
| 2022-01-08 19:00:00Sat., Jan 8 | North Carolina State | 5 - 2 | Liberty | LaHaye Ice Center | Recap |
| 2022-01-08 17:30:00Sat., Jan 8 | Delaware | 0 - 5 | Florida Gulf Coast | Hertz Arena | Recap |
| 2022-01-07 20:25:00Fri., Jan 7 | Liberty | 4 - 3 | North Carolina State | Wake Competition Center | Recap |
| 2022-01-07 20:00:00Fri., Jan 7 | Delaware | 1 - 8 | Florida Gulf Coast | Hertz Arena | Recap |
| 2021-12-11 19:50:00Sat., Dec 11 | Rowan | 19:50:00Postponed | Towson | Ice World | Recap |
| 2021-12-10 19:30:00Fri., Dec 10 | Rowan | 19:30:00Postponed | Towson | Ice World | Recap |
| 2021-12-05 15:30:00Sun., Dec 5 | Millersville | 5 - 6 | Stevenson | Reisterstown Sportsplex | Recap |
| 2021-12-03 00:00:59Fri., Dec 3 | Maryland | 5 - 3 | Towson | Ice World | Recap |
| 2021-11-21 15:15:00Sun., Nov 21 | Liberty | 5 - 3 | Lindenwood | Lindenwood | Recap |
| 2021-11-20 20:00:00Sat., Nov 20 | Rider | 7 - 2 | Montclair State | Montclair State Ice Arena | Recap |
| 2021-11-20 17:25:00Sat., Nov 20 | Liberty | 5 - 0 | Davenport | Lindenwood | Recap |
| 2021-11-19 18:31:18Fri., Nov 19 | Drexel | 4 - 5 | West Chester | Ice Line | Recap |
| 2021-11-19 14:15:00Fri., Nov 19 | Liberty | 1 - 4 | Mary | Lindenwood | Recap |
| 2021-11-13 00:00:27Sat., Nov 13 | Maryland | 3 - 3 | Virginia Tech | St. James | Recap |
| 2021-11-12 20:30:00Fri., Nov 12 | Marist | 0 - 15 | Penn State | Pegula Ice Arena | Recap |
| 2021-11-07 13:30:00Sun., Nov 7 | Miami (Ohio) | 2 - 3 | Liberty | LaHaye Ice Center | Recap |
| 2021-11-06 21:55:00Sat., Nov 6 | Miami (Ohio) | 1 - 5 | Liberty | LaHaye Ice Center | Recap |
| 2021-11-06 20:00:00Sat., Nov 6 | Rowan | 4 - 5 | Virginia Tech | Lancerlot | Recap |
| 2021-11-06 17:00:00Sat., Nov 6 | Drexel | 2 - 5 | Georgetown | The Gardens Ice House | Recap |
| 2021-11-06 16:30:00Sat., Nov 6 | Bentley | 2 - 5 | Penn State | Pegula Ice Arena | Recap |
| 2021-11-05 19:30:00Fri., Nov 5 | Bentley | 0 - 1 | Penn State | Pegula Ice Arena | Recap |
| 2021-10-31 22:00:00Sun., Oct 31 | Penn State | 5 - 3 | Virginia Tech | Lancerlot | Recap |
| 2021-10-31 15:00:00Sun., Oct 31 | Rowan | 6 - 2 | Stockton | Skate Zone Atlantic City | Recap |
| 2021-10-31 13:30:00Sun., Oct 31 | Trine | 1 - 2 | Liberty | LaHaye Ice Center | Recap |
| 2021-10-30 22:00:00Sat., Oct 30 | Penn State | 5 - 1 | UNC Wilmington | Wilmington Ice House | Recap |
| 2021-10-30 20:30:00Sat., Oct 30 | Drexel | 1 - 0 | Scranton | Revolution Ice Centre | Recap |
| 2021-10-30 19:30:00Sat., Oct 30 | UMass | 2 - 3 | Liberty | LaHaye Ice Center | Recap |
| 2021-10-30 15:45:00Sat., Oct 30 | Stevenson | 2 - 5 | Ohio | Bird Arena | Recap |
| 2021-10-29 22:00:00Fri., Oct 29 | Stevenson | 3 - 5 | Ohio | Bird Arena | Recap |
| 2021-10-29 22:00:00Fri., Oct 29 | Penn State | 2 - 3 | North Carolina State | Wake Competition Center | Recap |
| 2021-10-29 19:30:00Fri., Oct 29 | Florida Gulf Coast | 2 - 3 | Liberty | LaHaye Ice Center | Recap |
| 2021-10-29 18:15:00Fri., Oct 29 | Drexel | 1 - 4 | Delaware | Fred Rust Arena | Recap |
| 2021-10-29 17:30:00Fri., Oct 29 | Rider | 10 - 0 | Siena | Albany Country Ice Rink | Recap |
| 2021-10-24 09:00:00Sun., Oct 24 | Central Michigan | 2 - 3 | Drexel | Class of 1923 Arena | Recap |
| 2021-10-23 20:15:00Sat., Oct 23 | Siena | 1 - 5 | Rowan | Hollydell Ice Arena | Recap |
| 2021-10-23 15:20:00Sat., Oct 23 | Central Michigan | 0 - 4 | Rider | Loucks Ice Center | Recap |
| 2021-10-23 14:45:00Sat., Oct 23 | Drexel | 5 - 4 | Stockton | Skate Zone Atlantic City | Recap |
| 2021-10-22 21:00:00Fri., Oct 22 | Delaware | 6 - 2 | Georgetown | The Gardens Ice House | Recap |
| 2021-10-22 20:20:00Fri., Oct 22 | Central Michigan | 1 - 3 | Rider | Loucks Ice Center | Recap |
| 2021-10-16 20:15:00Sat., Oct 16 | Penn | 20:15:008:15 pm | Delaware | Fred Rust Arena | Recap |
| 2021-10-16 19:30:00Sat., Oct 16 | Mary | 6 - 1 | Liberty | LaHaye Ice Center | Recap |
| 2021-10-16 19:10:00Sat., Oct 16 | Ohio | 6 - 4 | Drexel | Class of 1923 Arena | Recap |
| 2021-10-16 16:15:00Sat., Oct 16 | Rider | 5 - 1 | Marist | Mid-Hudson Civic Center | Recap |
| 2021-10-15 21:15:00Fri., Oct 15 | Kutztown | 0 - 5 | Delaware | Fred Rust Arena | Recap |
| 2021-10-15 21:10:00Fri., Oct 15 | Marist | 0 - 4 | Rider | Loucks Ice Center | Recap |
| 2021-10-15 19:30:00Fri., Oct 15 | Mary | 1 - 4 | Liberty | LaHaye Ice Center | Recap |
| 2021-10-15 19:10:00Fri., Oct 15 | Ohio | 5 - 2 | Drexel | Class of 1923 Arena | Recap |
| 2021-10-14 19:30:00Thu., Oct 14 | Mary | 2 - 5 | Liberty | LaHaye Ice Center | Recap |
| 2021-10-09 19:10:00Sat., Oct 9 | Scranton | 1 - 0 | Drexel | Class of 1923 Arena | Recap |
| 2021-10-09 17:30:00Sat., Oct 9 | North Carolina State | 7 - 1 | Delaware | Fred Rust Arena | Recap |
| 2021-10-08 20:30:00Fri., Oct 8 | RPI | 4 - 5 | Rider | Loucks Ice Center | Recap |
| 2021-10-08 19:10:00Fri., Oct 8 | St. Joseph’s | 1 - 0 | Drexel | Class of 1923 Arena | Recap |
| 2021-10-08 18:15:00Fri., Oct 8 | North Carolina State | 6 - 4 | Delaware | Fred Rust Arena | Recap |
| 2021-10-03 13:00:00Sun., Oct 3 | Drexel | 3 - 4 | RPI | TBD | Recap |
| 2021-10-02 22:00:00Sat., Oct 2 | Stevenson | 1 - 7 | UNC Wilmington | Wilmington Ice House | Recap |
| 2021-10-02 20:15:00Sat., Oct 2 | New Jersey | 0 - 4 | Rowan | Hollydell Ice Arena | Recap |
| 2021-10-02 00:00:00Sat., Oct 2 | Drexel | 6 - 2 | Albany | TBD | Recap |
| 2021-10-01 20:20:00Fri., Oct 1 | NJIT | 2 - 7 | Rider | Loucks Ice Center | Recap |
| 2021-10-01 19:00:00Fri., Oct 1 | Stevenson | 0 - 12 | North Carolina State | Wake Competition Center | Recap |
| 2021-10-01 18:15:00Fri., Oct 1 | Rowan | 4 - 3 | Delaware | Fred Rust Arena | Recap |
| 2021-10-01 00:00:00Fri., Oct 1 | Drexel | 4 - 3 | Siena | TBD | Recap |
| 2021-09-26 15:00:00Sun., Sep 26 | Rider | 10 - 2 | Scranton | Revolution Ice Centre | Recap |
| 2021-09-25 20:40:00Sat., Sep 25 | Georgetown | 20:40:008:40 pm | Maryland | Prince William Ice Arena | Recap |
| 2021-09-25 19:00:00Sat., Sep 25 | Drexel | 4 - 3 | St. Joseph’s | Haverford Skatium | Recap |
| 2021-09-25 17:30:00Sat., Sep 25 | Delaware | 6 - 3 | Ohio | Bird Arena | Recap |
| 2021-09-24 21:10:00Fri., Sep 24 | Stevenson | 3 - 2 | Georgetown | The Gardens Ice House | Recap |
| 2021-09-24 20:20:00Fri., Sep 24 | Montclair State | 1 - 10 | Rider | Loucks Ice Center | Recap |
| 2021-09-24 17:30:00Fri., Sep 24 | Delaware | 2 - 4 | Ohio | Bird Arena | Recap |
| 2021-09-18 19:00:33Sat., Sep 18 | Indiana (Pa.) | 3 - 2 | Liberty | LaHaye Ice Center | Recap |
| 2021-09-17 19:30:00Fri., Sep 17 | Delaware | 3 - 2 | Towson | Ice World | Recap |
| 2021-09-12 12:50:00Sun., Sep 12 | Cincinnati | 4 - 11 | Rowan | Hollydell Ice Arena | Recap |
| 2021-09-11 10:30:00Sat., Sep 11 | Cincinnati | 5 - 4 | Delaware | Gold Arena | Recap |
| 2021-09-10 18:15:00Fri., Sep 10 | Cincinnati | 3 - 6 | Delaware | Fred Rust Arena | Recap |
